Clinical research backing SAINT®

Explore the peer-reviewed research, clinical trials, and real-world data that demonstrate SAINT’s impact on treatment-resistant depression.

MDD
Efficacy
Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial
MDD
Efficacy
Real-world evidence of SAINT® effectiveness in a heterogenous clinical population with psychiatric and medical comorbidities: A multicenter, open-label, community-based study
This analysis of the primary outcome includes the largest cohort of patients treated with SAINT to date. The results support previously reported rapid and significant improvements in depressive symptoms and extend these findings to a more clinically representative population.
Real-world evidence of SAINT® effectiveness in a heterogenous clinical population with psychiatric and medical comorbidities: A multicenter, open-label, community-based study

This analysis of the primary outcome includes the largest cohort of patients treated with SAINT…

A randomized controlled trial confirming efficacy, and an EEG study providing insight into mechanism of action and a potentially predictive biomarker of efficacy

World Psychiatry | Volume 25, Issue 1, Pages 105-116

High-dose spaced theta-burst TMS as a rapid-acting antidepressant in highly refractory depression

Brain | Volume 141, Issue 3, Page e18

Transcranial Magnetic Stimulation Parameter Space: Wide Open for Exploration

Biological Psychiatry | Volume 87, Issue 5, Pages 384-385

Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression

Research Summary Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression Authors  Nolan R. Williams, M.D.,…

Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial

Research summary Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial Authors Eleanor J. Cole,…

Targeted neurostimulation reverses a spatiotemporal biomarker of treatment-resistant depression

PNAS | Volume 120, Number 21

Network effects of Stanford Neuromodulation Therapy (SNT) in treatment-resistant major depressive disorder: a randomized, controlled trial

Nature Translational Psychiatry | 13, 240

An Avenue for Optimization of Theta Burst Stimulation Protocols? Comments on the FOUR-D Randomized Noninferiority Clinical Trial

American Journal of Psychiatry | Volume 181, Number 1

12 Months Sustained Remission from Depression using Personalized Continuation Therapy with SAINT®

Magnus Medical

Sustained Efficacy of Stanford Neuromodulation Therapy (SNT) in Open-Label Repeated Treatment

American Journal of Psychiatry | Volume 181, Number 1

Pilot study of stanford neuromodulation therapy (SNT) for bipolar depression

Brain Stimulation | Volume 17, Issue 2, 321-323

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