SAINT® is a faster path to lasting relief from depression

SAINT is the first and only FDA-cleared therapy to achieve remission in just five days.

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2 minutes · No cost · Confidential

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I’m seeking treatment
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I’m a healthcare professional

HOW SAINT WORKS

Treating depression in days, not weeks

SAINT is an advanced, targeted form of TMS therapy that uses precision neuromodulation to deliver rapid and lasting remission from Major Depressive Disorder (MDD) in an accelerated, 5-day treatment.

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Consultation
Meet with a Verified SAINT Provider to determine if SAINT is the right treatment for you.
A person holding a smartphone while on a telehealth video call with a healthcare professional.
fMRI brain scan
The fMRI scan creates a unique map of your brain’s neural circuitry in about 45 minutes, allowing SAINT to target your depression precisely.
A woman lying inside an MRI machine for a brain scan.
Personalized targeting
Our targeting algorithm uses the brain scan to map out the perfect location to deliver effective stimulation and treat your depression more precisely.
Side-by-side brain scans highlighting a specific targeted area.
Stimulation series
SAINT TMS treatment takes just five days. Each day consists of ten 10-minute sessions per day, with 50-minute breaks in between. Most people begin to feel a change in their mood within just a couple of days.
A woman sitting in a clinical chair receiving transcranial magnetic stimulation therapy.

THE FACTS

SAINT helps people with treatment-resistant depression get better, faster

Unlike conventional treatments that can take weeks or months to start working, SAINT can bring remission from depression symptoms in days.

Icon representing non-invasive treatment statistics.
days
of noninvasive, non-drug treatment (versus 6-9 weeks for standard TMS).
Icon representing trial participants.
%
of trial participants entered remission from their depression.
Icon representing the average days to remission.
days
to remission on average instead of weeks or months.
Icon representing clinic visits.
clinic visits
(versus 30-36 for standard TMS).

Cole EJ, Stimpson KH, Bentzley BS, et al.: Stanford Accelerated Intelligent Neuromodulation Therapy for treatment-resistant depression. Am J Psychiatry 2020; 177:716–726 2.Cole EJ, Phillips AL, Bentzley, BS, et al.: Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial. Am J Psychiatry 2022; 179:2, 132–141.

Depression treatment built with purpose, backed by science

We weren’t satisfied with the limits of traditional mental health care, so we set out to create a rapid-acting therapy grounded in innovation and personalization.

FDA cleared

SAINT received Breakthrough Device Designation, recognizing its potential to make life-changing treatment and remission more accessible to patients.

510(k) Clearance

Developed at Stanford

SAINT was developed by psychiatrists and neuroscientists at Stanford’s Brain Stimulation Lab, driven by a mission to reimagine psychiatry and transform how brain conditions are treated.

SAINT RCT

"A few days after I started the treatment…. I went out walking and shopping. Music sounded a little sweeter. I got hungry, which for me is a good sign because I have a hard time eating when I feel depressed or anxious. You feel changes the week you do the treatment."

Caroline N.
SAINT Patient

"There’s always been a concern that if it works fast, maybe it doesn’t work very well. But here we had a wonderful confluence of strong data showing that not only did people get their treatment done in a very short period of time, but that they had a very high probability of getting not just well, not just to response – but actually to remission."

Ian Cook, MD, DLFAPA
Founding Director & CEO, Los Angeles TMS Institute

"Because of SAINT, my daughter’s depression became so much less dangerous, the suicidal ideation has disappeared, and she hasn’t taken any antidepressants since. I believe this technology is the best, and I think more people need to know about it. This could be the best solution we have to cure MDD."

Sherri R.
Mother of a SAINT Patient

"SAINT removed the depression I carried for years. It did not erase my problems; it changed how my brain responds to them. That change is the difference between “barely coping” and actually living my life."

Alan S.
SAINT Patient

"I’m a scientist, I’m skeptical of a lot of things. And I don’t believe there’s any magic wand. We have to be really careful about how we interpret things, but SAINT is the closest thing I’ve seen to that magic wand."

Mohammed Ahmed, MD
Clinical Director, Salma Health

TESTIMONIALS

What people are saying about SAINT

Discover how science and compassion come together through the voices of patients and clinicians who’ve experienced SAINT firsthand.

Featured resources

Discover the science, clinical data, and patient success stories that show the power of SAINT depression therapy.

All research
Our blog
Blog
Depression

How Adult Depression Became More Visible in America

Two people experiencing similar symptoms may appear very differently in the data, depending on how their experiences…
Blog
Depression

The History of TMS: A Non-Invasive Breakthrough for Mental Health

Living with treatment-resistant depression can be an exhausting journey. Trying multiple antidepressant medications that fail to bring…
Blog
SAINT

Why SAINT® Is Setting New Standards for Patient Recovery

Those living with depression that hasn’t responded to medication already know the feeling: another prescription, another six-to-eight-week…
Blog
Depression

Clinical Depression vs. Bipolar Depression: Key Differences and Treatments

A note on this article: SAINT® for depression is FDA-cleared for the treatment of adults with treatment-resistant…

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Feeling better starts with finding the right care. Find a Verified SAINT Provider near you.

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